Frontier AI models have read the entire public internet, but they have never been inside an operating room. The hardest medical decisions exist only in surgical video, pathology labs, and clinical records.
Bolt Holdings is the reinforcement learning lab for clinical human data. We turn real robotic surgeries, patient consultations, and oncology archives into training environments where AI learns how master clinicians actually think and operate.
We partner directly with high-volume specialty clinics and private practices, where top surgeons own the entire patient journey from intake and imaging to surgery, pathology, and recovery.
Our medical and technical staff combines surgical, reproductive immunology, and oncology leadership with frontier AI pre- and post-training experience from Cohere, xAI, OpenAI, Alibaba, and Amazon.
Our ambition is to train AI that can diagnose, operate, and cure at the level of the world’s best surgeons and clinician-scientists, starting with women’s health, oncology, and surgical robotics.
Master Robotic Excision Surgeon & Reproductive Immunologist · MD, Univ. of Padova · NCI Italy, Georgetown & Columbia
Giorgio Vidali
Medical Advisor
Healthcare Chief Executive · University of Chicago · Former VP, Corporate Strategy & Transformation at AlixPartners & BCG
Reem Khattab
Technical Advisor
B.S. Biomedical Engineering · AI Training & Human Data Manager at Cohere, xAI, Handshake & Snorkel · Trained Cohere Coral, xAI Grok-3 & OpenAI GPT-class models
Current Focus
Endometriosis & Robotic Excision Surgery
Training models on the full diagnostic and operative arc of complex pelvic disease, connecting patient intakes, nurse triage, and pre-operative imaging to nerve-sparing robotic excision video and post-operative pathology.
Reproductive Immunology & Molecular Oncology
Modeling multi-step diagnostic and therapeutic reasoning across natural killer cell activity, cytokine profiling, IVF and recurrent miscarriage immunology, and molecular oncogene and tumor-suppressor pathways.
No Surprises Act Independent Dispute Resolution
Teaching agents to extract operative complexity from surgical records, audit payer underpayments, and synthesize federal arbitration briefs grounded in clinical necessity and statutory precedent.
Pelvic Congestion & Interventional Venous Mapping
Cross-specialty diagnostic reasoning separating vascular compression syndromes from gynecologic pathology across interventional radiology and minimally invasive pelvic surgery.
Benchmarks
EndoBench
Coming soon
Evaluating symptom-to-excision localization, fertility-sparing dissection plane selection, and operative CPT coding against board-certified surgeons.
OncoImmuno-Bench
Coming soon
Multi-step hypothesis verification across molecular oncogene, tumor-suppressor, and reproductive immunology cases.
Clinical-IDR-Bench
Coming soon
End-to-end federal No Surprises Act arbitration environment evaluating operative complexity extraction and qualifying payment amount rebuttal synthesis.